A woman holds a small bottle labeled with a “Vaccine COVID-19” sticker and a medical syringe in this illustration taken April 10, 2020. REUTERS/Dado Ruvic


Moderna announced Monday that they are starting stage three of the vaccine trials for COVID-19. The vaccine, mRNA-1273, is now in the COVE (Coronavirus Efficacy) stage in collaboration with the National Institutes of Health (NIH) as they helped fund the $1B trial. Stephane Bancel, CEO of Moderna, stated, “We are grateful to the efforts of so many inside and outside the company to get us to this important milestone. We are indebted to the participants and investigators who now begin the work of the COVE study itself. We look forward to this trial demonstrating the potential of our vaccine to prevent COVID-19, so that we can defeat this pandemic.”  

In this phase, Moderna will have up to 30,000 volunteers placed into one of two groups, where one receives mRNA-1273 and the other receives a saltwater placebo. The testing will take place in 89 centers around the United States. The conclusion date for the trial is currently unknown and will be based on the data given by the volunteers.  

Although many are glad to see progress in finding a vaccine, some are worried about the future price given that Moderna has received substantial funding from the United States government. Influencers voiced concern that the company will seek only profit when the vaccine will be released to the public, rather than selling it “at cost.” Others expressed hope this potential vaccine works, as Moderna is farther ahead on trial runs than most companies.


First Phase 3 clinical trial of a coronavirus vaccine in the United States begins – CNN – 7/27/2020
The investigational vaccine was developed by the biotechnology company Moderna and the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The trial is to be conducted at nearly 100 US research sites, according to Moderna. The first patient was dosed at a site in Savannah, Georgia.

The world’s biggest coronavirus vaccine study begins, a U.S. trial that will include 30,000 people to see if the shots really work – CNBC – 7/27/2020
The world’s biggest Covid-19 vaccine study got underway Monday with the first of 30,000 planned volunteers helping to test shots created by the U.S. government — one of several candidates in the final stretch of the global vaccine race.

Moderna’s Coronavirus Vaccine Begins Final-Stage Testing – The Wall Street Journal – 7/27/2020
Researchers plan to enroll 30,000 people across the U.S. in the last-stage, or phase 3, trial of the Moderna vaccine candidate. Results will determine whether two doses protects against symptomatic Covid-19, and should be cleared for widespread use.

Moderna launches coronavirus vaccine Phase 3 trial – Fox Business – 7/27/2020
Massachusetts biotech company Moderna launched Phase 3 of its coronavirus vaccine trial on Monday. Moderna anticipates enrolling 30,000 U.S. participants. There’s still no guarantee that the experimental vaccine, developed by the National Institutes of Health and Moderna, will really protect the participants.

Moderna skyrockets 11% after receiving another $472 million of funding, starting Phase 3 trial of COVID-19 vaccine – Business Insider – 7/27/2020
On Sunday, Moderna announced an additional round of $472 million in funding to “support late stage clinical development including the expanded Phase 3 study of the Company’s mRNA vaccine candidate (mRNA-1273) against COVID-19,” according to a statement.


NIH on Twitter, 7/27/2020: A Phase 3 clinical trial of investigational vaccine mRNA-1273 to prevent #COVID19, co-developed by #NIH @NIAIDNews and @Moderna, has begun. The multisite trial will assess preventive power, enrolling 30k+ volunteers.

Emerald Robinson ✝️  on Twitter, 7/27/2020: Why is the Trump Administration touting a vaccine from Moderna? Moderna’s vaccine uses cells from aborted babies. That’s a dealbreaker with pro-lifers. Perhaps the Trump Administration should get in touch with some Trump supporters.

Melissa Jo Peltier on Twitter, 7/27/2020: So we taxpayers fund Moderna’s vaccine research. We fund their clinical trials. 30,000 Americans volunteer as guinea pigs… …and Moderna gets to gouge us on the final vaccine if/when it comes to market. Yeah, sounds fair.

Nicole Saphier, MD on Twitter, 7/27/2020: Moderna begins 30,000 participant Phase 3 COVID19 vaccine trial TODAY. The trial will evaluate safety in various demographics & will evaluate ability to prevent or lessen severity of infection. This may provide the info we have been waiting for regarding antibodies and immunity.

Reuters on Twitter, 7/27/2020: Dr. Anthony Fauci says aims to finish enrollment in Moderna’s late-stage COVID-19 vaccine trial by the end of summer

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